The copper-colored eyes that finally named the shunt nobody could find

An internal medicine specialist saw what a year of general-practice visits didn't: the eye color that tracks with a rare liver defect.

The copper-colored eyes that finally named the shunt nobody could find

Photo: Sam Grozyan · Unsplash

Darren Bass sat in exam rooms for over a year watching veterinarians run tests on a stray kitten he'd named Spot, and nobody could tell him why she stayed sick.

The detail that broke the case

Dr. Whitney Nelson, an internal medicine specialist at Pet Emergency Clinic and Referral Center in Spokane, reviewed Spot's medical history and symptoms and saw something that pointed her in the right direction: copper-colored eyes. In cats, that trait is sometimes associated with portosystemic shunts, a rare congenital liver defect where blood bypasses the liver instead of being filtered. Nelson ordered an ultrasound. It confirmed the shunt.

Portosystemic shunts are uncommon in cats and present with symptoms across multiple organ systems, poor growth, weight loss, appetite changes, neurological problems, which is why they're hard to catch unless you're looking. Bass had brought Spot in repeatedly for what looked like a persistent upper respiratory infection. The symptoms would improve, then come back worse. No one had put the pieces together until Nelson saw the eye color and knew what to look for.

The surgery, and what it buys

Nelson referred Spot to Washington State University's Veterinary Teaching Hospital for surgical correction. Dr. Boel Fransson, a board-certified surgeon, placed a cellophane band around the abnormal blood vessel. The band gradually closes the vessel over time, letting the liver adjust to increased blood flow.

Fransson said some pets with portosystemic shunts can be managed on specialized diets and medication, but surgery offers the best shot at a normal lifespan. The procedure requires extensive training and experience. If the vessel fully attenuates and the cat is young and otherwise healthy, Fransson's experience is cats can do quite well.

Bass said WSU's Good Samaritan Fund helped cover the cost. The fund provides financial assistance to clients facing unexpected hardship while their animals receive care at the teaching hospital. Without surgery, the hospital told him Spot probably had a few more years. Now she's gaining weight and growing stronger.

What we're watching

The clinical pattern here is narrow but real: portosystemic shunts in cats are rare enough that they hide behind more common diagnoses until someone who's seen the presentation before recognizes it. Copper-colored eyes were the tell in this case. The source doesn't say whether that's a reliable marker across all feline shunt cases, but it was enough to prompt Nelson to order the ultrasound that confirmed it.

The referral-pattern read is what we'd flag for practices. This case moved through multiple general-practice and urgent-care stops before an internist with pattern-recognition experience made the call. That's the designed flow, not every rare diagnosis needs to land on the first visit, but the system has to get the case to someone who's seen the pattern before it costs the cat years of quality life. Bass spent over a year frustrated. It took a specialist to read the symptoms.

Our read: the teaching-hospital piece matters here too. Fransson said the cellophane-band procedure requires extensive training and experience, which means most practices are referring this surgery out regardless. The question for a general practitioner isn't whether to attempt the repair, it's whether to recognize when vague multi-system symptoms in a young cat warrant a specialist consult sooner rather than later. We're not saying every URI that doesn't fully resolve is a shunt, the condition is uncommon, but when nothing else is landing and the patient keeps cycling back, the case is telling you something.

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The landing

Bass found Spot outside his home on a cold October night in 2024, brought her in thinking he'd rehome her, and kept her instead. He said at the time he was struggling to find work and wasn't sure he'd stay housed, and the kitten that needed someone ended up helping him too. Now Spot's recovering from surgery that should give her a normal lifespan, and Bass said his hope is to someday repay the Good Samaritan Fund's help by helping someone else.

The copper eyes were the clue. It took over a year and a referral to an internist before anyone knew what they meant.

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Source: Washington State College of Veterinary Medicine News

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